This is my fav Dimarzio a the moment, the midrange is so crunchy its insane.
Mark Morton from Lamb of God uses Breeds in his live guitars so I figured I'd try them out.
I put the breed bridge in my mahogany superstrat 6 months ago and it added so much crunch to my tone. The pickup is warm enough that i don't really need to switch to the neck pickup for cleans.
With pickups like the D Activator and Super D i find that no matter how clean or distorted they are they maintain their tonality, not the case with the Breed it almost feels like a different pickup depending on how much gain I use. It sounds just as awesome for classic rock as it does for death metal, which isn't the case for any other pickup I've tried. With medium gain its warm and crunchy, high gain makes the lows tighter and pinch harmonics are easy to get and sustain.
This is the only pickup Ive ever heard convincing AC/DC tones out of in a superstrat. Its also great for LOG style metal tones (not scooped), I don't scoop my mids since I like to be heard over the drums, the breed adds even more depth to the midrange and especially accents alternate picking.
If you play rock and metal and like midrangey tones more than scooped ones I recommend trying the breed.